Antibacterial and antibiofilm activities of extract Capsicum annuum L on the growth and biofilm formation of common pathogenic strains

In the environment, many microorganisms coexist in communities competing for resources, and they are often associated as biofilms. The investigation of bacterial ecology and interactions may help to improve understanding of the ability of biofilms to persist. In this study, the antibacterial and antibiofilm activities of extract Capsicum annuum L on the growth and biofilm formation of common pathogenic strains that isolates from the urinary tractinfection were examined. All 6 strains (2 Klebsiellapneumoniae, 2 Pseudomonas aeruginosa and 2 E.coli) isolated from urine culture of hospitalized patients (Amir Al-Momenin Hospital, Zabol, southeastern Iran) suffered from urinary tract infections during a period of one months were evaluated. The ESBL producing Klebsiellapneumoniae, Pseudomonas aeruginosa and Ecoliwere evaluated by disk diffusion test and growth and biofilm formation of common pathogenic strains were determinedmicrotiterplate method. The results showed that different concentration of extract plant had significant effects on the bacterial growth and even at 5and 10mg/ml showed the most restrain in the biofilm formation of the isolate. Furthermore, the data demonstrate the biocontrol potential of Capsicum annuum L on the plank tonic growth and information biofilm of Klebsiellapneumoniae, Pseudomonas aeruginosa and Ecoli and can suggest it as a suitable biocide for the recirculating urine systems.